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Try the Cannify Quiz and get your personalized report. You can learn how to use cannabis to get the effect you want from science-based information with included list of referenced studies. It’s free!

 

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Where does CBD come from?

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When we decarboxylate CBDA, we get CBD. Read more about CBD on the Chemistry of Cannabis Plants page.
 

 

What’s the difference between topical and transdermal products?

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The main difference between topical and transdermal products is in the level of medicine penetration. Transdermal products penetrate epidermis and dermis and enter the blood circulation, while topical products generally do not reach layers below the epidermis. Read more on the Topical vs. Transdermal page. Learn how cannabis compounds get absorbed through the skin on the Absorption page, where you can also read about the absorption via other administration routes.

 

 

What are CB1 and CB2 receptors?

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The endocannabinoid system consists of two types of receptors which can be found in different organs in the body. Cannabis compound THC binds to these receptors yielding different effects. Learn more about endocannabinoid receptors in our Education section.

 

 

Cannabis flower – is it safe?

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Just like with any other drug, taking cannabis comes with certain risks. Many people experience (serious) side-effects, like drowsiness and panic attacks, which are often caused by wrong dosing. Always consult your health care provider before cannabis use. Learn more about cannabis products in our Education section.

 

 

Cannabis concentrates and extracts – how are they made?

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As an alternative to using cannabis in a raw flower form, active compounds and flavor compounds can be extracted and isolated from the cannabis plant. A variety of cannabis extraction techniques is used to prepare the desired compounds into a form appropriate for various administration techniques. Find out more about each method on our Extraction techniques page.

 

 

Cannabis flower – how is it used?

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Cannabis flower can be used in various ways. It is usually orally ingested or inhaled. Each administration method has a different effect onset, duration, and strength. To find out more about cannabis products and how they are used, check out our Cannabis products page.

 

 

Cannabis flower – how is it made?

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Cannabis flower can be consumed in several ways. However, flowers first need to be dried for preservation and to change and retain the smell. To find out more about cannabis products and how they are made, check out our Cannabis products page.

 

 

Inhalation vs. Ingestion

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Cannabis inhalation and cannabis ingestion trigger different chemical processes in our bodies. As a result, the strength of the effects we experience differs greatly. This is, for an important part, due to one of the phases of Pharmacokinetics called metabolism which transforms cannabis compounds, such as THC, and exerts various effects.

 

 

Marijuana vs. Hemp

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Marijuana and Hemp are both cannabis. What makes them different from a legal perspective is the amount of THC. The threshold that separates these two cannabis species was chosen arbitrarily. Read our page Marijuana vs. hemp for more.

 

 

Will CBD make you feel high?

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CBD does not make you feel ‘high’. Feeling ‘high’ is a euphoric effect. It is specifically associated with cannabis use. Many recreational users want this effect, whereas many medical users don’t.

 

THC is a well-known cannabis compound that makes you feel high upon binding to CB1 receptors in the brain. Receptors are places where compounds that bind can trigger an effect. CBD does not bind to CB1 receptors the same way THC does. Therefore, as opposed to THC, CBD does not make you feel high. However, CBD is psychoactive, meaning that it has effects on mental processes. Considering that CBD influences, for example, anxiety, it falls under psychoactive substances.1, 2, 3, 4, 5

 

Further details and studies on this matter can be found on Cannify’s Education Pages, which include many other useful topics from the world of cannabis.

 

References:
  1. Zuurman, Lineke; Ippel, Annelies E.; Moin, Eduard; Gerven, Joop M. A. Van (2008). Biomarkers for the effects of cannabis and THC in healthy volunteers.
  2. Pertwee, R. G. (2006). The pharmacology of cannabinoid receptors and their ligands: an overview. International Journal of Obesity, 30(S1), S13--S18.
  3. Klumpers, Linda E.; Fridberg, Marianne; de Kam, Marieke L.; Little, Paul B.; Jensen, Niels Ole; Kleinloog, Hendrik D.; Elling, Christian E.; van Gerven, Joop M. A. (2013). Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects. British Journal of Clinical Pharmacology, 76(6), 846--857.
  4. Crippa, J. A. S.; Derenusson, G. N.; Ferrari, T. B.; Wichert-Ana, L.; Duran, Fabio L. S.; Martin-Santos, R.; Simoes, M. V.; Bhattacharyya, S.; Fusar-Poli, P.; Atakan, Z.; Filho, A. S.; Freitas-Ferrari, M. C.; McGuire, Philip K.; Zuardi, A. W.; Busatto, G. F.; Hallak, J. E. C. (2011). Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report. Journal of Psychopharmacology, 25(1), 121--130.
  5. Martin-Santos, R.; A. Crippa, J.; Batalla, A.; Bhattacharyya, S.; Atakan, Z.; Borgwardt, S.; Allen, P.; Seal, M.; Langohr, K.; Farre, M.; Zuardi, A. W.; K. McGuire, P. (2012). Acute Effects of a Single, Oral dose of d9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) Administration in Healthy Volunteers. Current Pharmaceutical Design, 18(32), 4966--4979.